[Charcot-Marie-Tooth disorders: past, today and tomorrow].

Abstract excerpt

Both intra- and interfamiliar variability of the clinical course of Charcot-Marie-Tooth disorders (CMT) were reported in the descriptions of the CMT disease in the 19th century. In the 1950s, it was shown that CMT disorders may be classified into two main groups i.e. CMT 1 and 2 on the basis of motor nerve conduction velocity in the motor fibers of the median nerve (MNCV=38 m/s). With the neuropathological...

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