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Article

Genetic analysis of MEFV gene pyrin domain in patients with Behçet's disease.

Mediators of inflammation - 1 Jan 2006

Dursun Ahmet, Durakbasi-Dursun Hatice Gul, Zamani Ayse Gul, Gulbahar Zerrin Gülin, Dursun Recep, Yakicier Cengiz

Abstract excerpt

OBJECTIVES: Behçet's disease (BD) is a systemic vasculitis with recurrent oral and genital ulcers and uveitis. MEFV gene, which is the main factor in familial Mediterranean fever (FMF), is also reported to be a susceptibility gene for BD. The pyrin domain of MEFV gene is a member of death-domain superfamily and has been proposed to regulate inflammatory signaling in myeloid cells. This study was designed to...

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Share to Behcet Syndrome
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymerase Chain Reaction

Share to Protein Structure, Tertiary

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 16951489
DOI: 10.1155/MI/2006/41783
PMCID: PMC1592598

Genes

MEFV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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