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[Predominance and evolution of BLA(SHV) genes in Tunisian hospital isolates of Klebsiella pneumoniae].

Archives de l'Institut Pasteur de Tunis - 1 Jan 2005

Ben-Hamouda T, Ben-Mahrez K

Abstract excerpt

Extended-spectrum beta-lactamases (ESBLs)produced by clinical strains of Klebsiella pneumoniae were investigated, using isoelectric-focusing and DNA amplification followed by sequencing. A predominance of SHV variants was found. Sequencing identified the genes for the SHV-2a and -12 enzymes, suggesting direct evolution of SHV-12 from SHV-2a.

Topics

DNA, Bacterial
Evolution, Molecular
Genetic Variation
Hospitals, Urban
Humans
Isoelectric Focusing
Klebsiella Infections
Klebsiella pneumoniae
Molecular Epidemiology
Mutation
Nucleic Acid Amplification Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Transformation, Bacterial

Tunisia

beta-Lactamases

Source

Identifiers

PMID: 16929752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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