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Article

Molecular Evolution of the tprC, D, I, K, G, and J Genes in the Pathogenic Genus Treponema

10 Aug 2006

Abstract excerpt

We investigated the evolution of 6 genes from the Treponema pallidum repeat (tpr) gene family, which encode potential virulence factors and are assumed to have evolved through gene duplication and gene conversion events. The 6 loci (tprC, D, G, J, I, and K) were sequenced and analyzed in several members of the genus Treponema, including the 3 subspecies of human T. pallidum (T. pallidum subsp. pallidum, pertenue,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16926243
DOI: 10.1093/molbev/msl092

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