Article
Site-directed mutagenesis of a plant viral satellite RNA changes its phenotype from ameliorative to necrogenic.
Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1990
Sleat D E, Palukaitis P
Abstract excerpt
Comparison of the nucleotide sequences of cucumber mosaic virus (CMV) satellite RNAs, which induce necrosis on tomatoes, reveals a highly conserved region within their 3' halves. The sequence of WL1 satellite (WL1-sat) RNA, which attenuates CMV symptoms on tomatoes, differs from all necrogenic satellite RNAs at three nucleotide positions within this conserved region. These nucleotides were progressively mutated...
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