Article
Clarification of pathway-specific inhibition by Fourier transform ion cyclotron resonance/mass spectrometry-based metabolic phenotyping studies.
Plant physiology - 1 Oct 2006
Oikawa Akira, Nakamura Yukiko, Ogura Tomonori, Kimura Atsuko, Suzuki Hideyuki, Sakurai Nozomu, Shinbo Yoko, Shibata Daisuke, Kanaya Shigehiko, Ohta Daisaku
Abstract excerpt
We have developed a metabolic profiling scheme based on direct-infusion Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR/MS). The scheme consists of: (1) reproducible data collection under optimized FT-ICR/MS analytical conditions; (2) automatic mass-error correction and multivariate analyses for metabolome characterization using a newly developed metabolomics tool (DMASS software); (3)...
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