Article
The association of DNA sequence variation at the MAOA genetic locus with quantitative behavioural traits in normal males.
Human genetics - 1 Nov 2006
Rosenberg Shai, Templeton Alan R, Feigin Paul D, Lancet Doron, Beckmann Jacques S, Selig Sara, Hamer Dean H, Skorecki Karl
Abstract excerpt
Monoamine oxidase A (MAOA) catalyses the oxidative deamination of biogenic amines including neurotransmitters, mainly norepinephrine and serotonin in the brain and peripheral tissues. A nonsense mutation in the gene was shown to be involved in a rare X-linked behavioural syndrome, which includes impaired impulse control, aggression and borderline mental retardation (Brunner syndrome). Several recent studies have...
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