Article
Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes.
Autoimmunity - 1 Jun 2006
Cabrera-Rode Eduardo, Molina Gisela, Arranz Celeste, Vera Manuel, González Pedro, Suárez Rolando, Prieto Mirta, Padrón Saúl, León Rafael, Tillan Juana, García Igrid, Tiberti Claudio, Rodríguez Olga María, Gutiérrez Antonio, Fernández Tamara, Govea Amparo, Hernández José, Chiong Dania, Domínguez Emma, Di Mario Umberto, Díaz-Díaz Oscar, Díaz-Horta Oscar
Abstract excerpt
BACKGROUND: Nicotinamide has been used with success to prevent type 1 diabetes in animal models and humans. This vitamin B3 derivative has attracting effects on beta-cell protection and regeneration. AIM/HYPOTHESIS: To evaluate the effect of standard nicotinamide administration on type 1 diabetes prevention in first degree relatives of persons with type 1 diabetes as well as on the concentrations of...
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