Article
Research actuality in the genetics of stroke.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2000
Orlacchio Antonio, Bernardi Giorgio
Abstract excerpt
Stroke can be viewed as a paradigm for late-onset, complex polygenic diseases. There are two main clinical phenotypes for stroke: ischemic stroke, responsible for 80-90% of stroke events, and hemorrhagic stroke, responsible for the remaining 10-20%. Stroke may either be the outcome of a number of monogenic disorders or, more commonly, a polygenic multifactorial disease. Cerebral autosomal dominant arteriopathy...
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