Article
An Arabidopsis homologue of human seven-in-absentia-interacting protein is involved in pathogen resistance.
Molecules and cells - 30 Jun 2006
Kim Youn-Sung, Ham Byung-Kook, Paek Kyung-Hee, Park Chung-Mo, Chua Nam-Hai
Abstract excerpt
Human seven-in-absentia (SIAH)-interacting protein (SIP) is a component of the E3 ligase complex targeting beta-catenin for destruction. Arabidopsis has one SIP protein (AtSIP) with 32% amino acid sequence identity to SIP. To investigate the functions of AtSIP, we isolated an atsip knockout mutant, and generated transgenic plants overexpressing AtSIP. The growth rates and morphologies of the atsip and transgenic...
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