Article
Neutralizing antibody responses of pigs infected with natural GP5 N-glycan mutants of porcine reproductive and respiratory syndrome virus.
Viral immunology - 1 Jan 2006
Faaberg Kay S, Hocker Jason D, Erdman Matthew M, Harris D L Hank, Nelson Eric A, Torremorell Montserrat, Plagemann Peter G W
Abstract excerpt
In order to assess the effect of the N-glycans associated with the GP5 neutralization epitope of porcine reproductive and respiratory syndrome virus (PRRSV) on the neutralizing antibody (Ab) response of swine, groups of young pigs were infected with PRRSV strains differing in N-glycosylation pattern. The humoral immune response to strain VR-2332, harboring four potential N-glycan sites, was compared to that of...
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