Article
Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii.
Proceedings of the National Academy of Sciences of the United States of America - 5 Jul 2006
Boyle Jon P, Rajasekar Badri, Saeij Jeroen P J, Ajioka James W, Berriman Matthew, Paulsen Ian, Roos David S, Sibley L David, White Michael W, Boothroyd John C
Abstract excerpt
Toxoplasma gondii, an obligate intracellular protozoan of the phylum Apicomplexa, is estimated to infect over a billion people worldwide as well as a great many other mammalian and avian hosts. Despite this ubiquity, the vast majority of human infections in Europe and North America are thought to be due to only three genotypes. Using a genome-wide analysis of single-nucleotide polymorphisms, we have constructed a...
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