Article
Phenotypic variation in constitutional delay of growth and puberty: relationship to specific leptin and leptin receptor gene polymorphisms.
European journal of endocrinology - 1 Jul 2006
Banerjee Indraneel, Trueman Julie A, Hall Catherine M, Price David A, Patel Leena, Whatmore Andrew J, Hirschhorn Joel N, Read Andrew P, Palmert Mark R, Clayton Peter E
Abstract excerpt
OBJECTIVES: Constitutional delay of growth and puberty (CDGP) is a variant of normal pubertal timing and progress, often with dominant inheritance. It is likely that one or more genes will be associated with CDGP. Possible candidates are the leptin (L) and the leptin receptor (LR) genes, as the leptin axis links nutritional status to pubertal development. This study has assessed whether a) L or LR gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.