Article
Detecting genotype-environment interaction in monozygotic twin data: comparing the Jinks and Fulker test and a new test based on Marginal Maximum Likelihood estimation.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Jun 2006
van der Sluis Sophie, Dolan Conor V, Neale Michael C, Boomsma Dorret I, Posthuma Danielle
Abstract excerpt
This article is concerned with the power to detect the presence of genotype by environment interaction (G x E) in the case that both genes and environment feature as latent (i.e., unmeasured) variables. The power of the test proposed by Jinks and Fulker (1970), which is based on regressing the absolute difference between the scores of monozygotic twins on the sums of these scores, is compared to the power of an...
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