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Article

Crystal Structure of the Rabies Virus Nucleoprotein-RNA Complex

15 Jun 2006

Abstract excerpt

Negative-strand RNA viruses condense their genome into a helical nucleoprotein-RNA complex, the nucleocapsid, which is packed into virions and serves as a template for the RNA-dependent RNA polymerase complex. The crystal structure of a recombinant rabies virus nucleoprotein-RNA complex, organized in an undecameric ring, has been determined at 3.5 angstrom resolution. Polymerization of the nucleoprotein is...

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PMID: 16778023
DOI: 10.1126/science.1125280

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