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Article

Insertions in the prion protein gene in atypical dementias.

Experimental neurology - 1 May 1991

Owen F, Poulter M, Collinge J, Leach M, Shah T, Lofthouse R, Chen Y F, Crow T J, Harding A E, Hardy J

Abstract excerpt

A number of mutations have been demonstrated in the open reading frame (ORF) of the prion protein (PrP) gene in patients with familial Creutzfeldt-Jakob disease or Gerstmann-Sträussler syndrome. On the basis of detecting an insertion in the ORF of the PrP gene in a patient originally suspected to be suffering from familial Alzheimer-type dementia, we screened 101 individuals with atypical dementias for the known...

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Identifiers

PMID: 1674696
DOI: 10.1016/0014-4886(91)90075-n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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