Article
Normal serum alanine concentration differentiates transient neonatal lactic acidemia from an inborn error of energy metabolism.
Biology of the neonate - 1 Jan 2006
Morava Eva, Hogeveen Marije, De Vries Maaike, Ruitenbeek Wim, de Boode Willem-Pieter, Smeitink Jan
Abstract excerpt
BACKGROUND: Elevated blood lactate levels are common in the critically ill neonate; however, sometimes they are difficult to interpret. Persistent or recurrent lactic acidemia might point to an inborn error of metabolism, like disturbances of the oxidative phosphorylation. Chronic lactic acidemia results in increased serum alanine levels. Serum alanine levels in newborns with transient lactic acidemia have not...
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