Article
Ethanol-induced fetal dysmorphogenesis in the mouse is diminished by high antioxidative capacity of the mother.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Aug 2006
Wentzel Parri, Eriksson Ulf J
Abstract excerpt
Intrauterine exposure to ethanol causes embryonic and fetal maldevelopment. Oxidative stress in mother and offspring has been suggested to be part of the teratogenic mechanism of ethanol. Here we aimed to assess the importance of maternal and fetal antioxidative capability for the risk of dysmorphogenesis in the offspring. We used male and female mice with different levels of superoxide dismutase (SOD)...
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