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Article

Psychiatric comorbidity and progression in drug use in adult male twins: implications for the design of genetic association studies.

Addictive behaviors - 1 Jun 2006

Todorov Alexandre A, Lynskey Michael T, Grant Julia D, Scherrer Jeffrey F, Todd Richard D, Bucholz Kathleen Keenan

Abstract excerpt

Psychiatric comorbidity with drug dependence has been widely documented. In the present study, we reanalyze DSM-III-R diagnostic data on middle-aged male twin pairs from the VETR study using latent class methods. We identify four subtypes based on 15 diagnostic categories. We then show that these subtypes are strongly associated with differential rates of transitions in drug use histories, with increased risks in...

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PMID: 16713123
DOI: 10.1016/j.addbeh.2006.03.046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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