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Article

Proteomic identification of potential target proteins regulated by an ASK1-mediated proteolysis pathway.

Cell research - 1 May 2006

Wang Xiaofeng, Ni Weimin, Ge Xiaochun, Zhang Jiejin, Ma Hong, Cao Kaiming

Abstract excerpt

The ASK1 (ARABIDOPSIS SKP1-LIKE) protein is a critical component of the SCF (Skp1-Cullin-F box protein) ubiquitin ligase complexes that recruit target proteins for degradation by the 26S proteosome. To investigate proteins that are affected by the ASK1-mediated proteolysis pathway in Arabidopsis flowers, we compared the proteomes of the Arabidopsis wild type and ask1 mutant flower buds using two-dimensional...

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Source

Identifiers

PMID: 16699544
DOI: 10.1038/sj.cr.7310060

Genes

SKP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Proteomic identification of potential target proteins regulated by an ASK1-mediated proteolysis pathway.PMID 16699544Read ↗

Proteomics and transcriptomics analyses of Arabidopsis floral buds uncover important functions of ARABIDOPSIS SKP1-LIKE1.Semantic proximity Read ↗

Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis.Semantic proximity Read ↗

Expression and interaction analysis of Arabidopsis Skp1-related genes.Semantic proximity Read ↗

The ASK1 and ASK2 genes are essential for Arabidopsis early development.Semantic proximity Read ↗

Generation of a fertile ask1 mutant uncovers a comprehensive set of SCF-mediated intracellular functions.Semantic proximity Read ↗

Conservation and divergence of ASK1 and ASK2 gene functions during male meiosis in Arabidopsis thaliana.Semantic proximity Read ↗

SKP1 is involved in abscisic acid signalling to regulate seed germination, stomatal opening and root growth in Arabidopsis thaliana.Semantic proximity Read ↗

Regulated proteolysis and plant development.Semantic proximity Read ↗

The ASK1 gene regulates development and interacts with the UFO gene to control floral organ identity in Arabidopsis.Semantic proximity Read ↗

RNAi-mediated silencing of the Arabidopsis thaliana ULCS1 gene, encoding a WDR protein, results in cell wall modification impairment and plant infertility.Semantic proximity Read ↗

Regulation of flower development in Arabidopsis by SCF complexes.Semantic proximity Read ↗

The AtRbx1 protein is part of plant SCF complexes, and its down-regulation causes severe growth and developmental defects.Semantic proximity Read ↗

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