Article
CD34+/CD133- circulating endothelial precursor cells (CEP): characterization, senescence and in vivo application.
Experimental gerontology - 1 Jun 2006
Untergasser Gerold, Koeck Ruth, Wolf Dominik, Rumpold Holger, Ott Harald, Debbage Paul, Koppelstaetter Christian, Gunsilius Eberhard
Abstract excerpt
Circulating endothelial precursor cells (CEP) are interesting candidates for the treatment of ischemic diseases and for tumor targeting/imaging. We isolated a homogeneous population of CEP from CD34(+)/CD133(-) cells of peripheral blood that can be expanded easily on collagen-type-I coated plastic. CEP displayed a phenotype of mature endothelial cells (vWF, CD31, CD34, VEGF-R2, CD105, CD146) similar to that of...
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