Progress toward the isolation and characterization of the genes causing neurofibromatosis.

doi:10.1111/j.1750-3639.1990.tb00636.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Progress toward the isolation and characterization of the genes causing neurofibromatosis.

Brain pathology (Zurich, Switzerland) - 1 Sept 1990

Menon A G, Gusella J F, Seizinger B R

Abstract excerpt

Neurofibromatosis 1 and neurofibromatosis 2 are clinically distinct autosomal dominant disorders that affect an estimated 1.5 million individuals throughout the world. The genetic defect in each disorder has been mapped to different chromosomes, NF1 to chromosome 17 and NF2 to chromosome 22. Prog...

Topics

Chromosome Aberrations
Chromosome Mapping
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 22
Cloning, Molecular
Gene Expression Regulation, Neoplastic
Genes, Dominant
Genes, Neurofibromatosis 1
Genes, Neurofibromatosis 2
Genetic Markers
Humans
Mutation
Neurofibromatosis 1
Neurofibromatosis 2
Parents
Prevalence

Source

Open in PubMed

Identifiers

PMID: 1669691
DOI: 10.1111/j.1750-3639.1990.tb00636.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1669691-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics