Article
[A comparative analysis of tuberculosis susceptibility genetic make-up in Tuvinians and Russians].
Molekuliarnaia biologiia - 1 Jan 2000
Freĭdin M B, Rudko A A, Kolokolova O V, Ondar E A, Strelis A K, Puzyrev V P
Abstract excerpt
The results of the first Russian study of polymorphisms of tuberculosis (TB) susceptibility genes SLC11A1, VDR, IL12B, IL1B, IL1RN in Tuvinians from Tuva Republic and Russians from Tomsk city are presented. In Tuvinians, as compared with Russians, the significantly higher prevalence of potentially disease-associated alleles of the genes studied was shown: SLC11A1*543N (0.139 and 0.043, respectively, p = 4.6E-5),...
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