Regulation of immune responses by T cells with different cytokine secretion phenotypes: role of a new cytokine, cytokine synthesis inhibitory factor (IL10).

doi:10.1159/000235340

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Article

Regulation of immune responses by T cells with different cytokine secretion phenotypes: role of a new cytokine, cytokine synthesis inhibitory factor (IL10).

International archives of allergy and applied immunology - 1 Jan 1991

Mosmann T R

Abstract excerpt

Subsets of T cells, defined by the patterns of cytokines that they secrete, show important functional differences, and appear to be at least partly responsible for the different immune responses induced by various pathogens. Two very distinct subsets, TH1 and TH2, are mutually inhibitory, and a n...

Topics

Animals
Antibodies, Monoclonal
Cytokines
Herpesvirus 4, Human
Humans
Interleukin-10
Mice
Parasitic Diseases
Phenotype
T-Lymphocyte Subsets

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