Article
A design for cancer case-control studies using only incident cases: experience with the GEM study of melanoma.
International journal of epidemiology - 1 Jun 2006
Begg Colin B, Hummer Amanda J, Mujumdar Urvi, Armstrong Bruce K, Kricker Anne, Marrett Loraine D, Millikan Robert C, Gruber Stephen B, Culver Hoda Anton, Zanetti Roberto, Gallagher Richard P, Dwyer Terrence, Rebbeck Timothy R, Busam Klaus, From Lynn, Berwick Marianne
Abstract excerpt
BACKGROUND: The population-based case-control study is not suited to the evaluation of rare genetic (or environmental) factors. The use of a novel case-control design in which cases have second primaries and controls are cancer survivors has been proposed for this purpose. METHODS: We report results from an international study of melanoma that involved population-based ascertainment of incident cases of second or...
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