Article
Challenges of detecting directional selection after a bottleneck: lessons from Sorghum bicolor.
Genetics - 1 Jun 2006
Hamblin Martha T, Casa Alexandra M, Sun Hong, Murray Seth C, Paterson Andrew H, Aquadro Charles F, Kresovich Stephen
Abstract excerpt
Multilocus surveys of sequence variation can be used to identify targets of directional selection, which are expected to have reduced levels of variation. Following a population bottleneck, the signal of directional selection may be hard to detect because many loci may have low variation by chance and the frequency spectrum of variation may be perturbed in ways that resemble the effects of selection. Cultivated...
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