Article
Marburg I polymorphism of factor VII-activating protease and risk of recurrent venous thromboembolism.
Thrombosis and haemostasis - 1 Jan 2006
Gulesserian Talin, Hron Gregor, Endler Georg, Eichinger Sabine, Wagner Oswald, Kyrle Paul A
Abstract excerpt
Whether a single nucleotide polymorphism (1601 G > A) in the factor VII-activating protease gene (FSAP Marburg I) is a risk factor for venous thromboembolism (VTE) is unclear. We investigated the relevance of the variant with respect to recurrentVTE. 854 patients with a first unprovoked VTE were followed for an average of 41 months after discontinuation of anticoagulation. Study endpoint was symptomatic recurrent...
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