Inhibitory autocrine factors produced by the mesenchyme-derived hair follicle dermal papilla may be a key to male pattern baldness

Abstract excerpt

BACKGROUND: Androgenetic alopecia, or male pattern baldness, is a common, progressive disorder where large, terminal scalp hairs are gradually replaced by smaller hairs in precise patterns until only tiny vellus hairs remain. This balding can cause a marked reduction in the quality of life. Although these changes are driven by androgens, most molecular mechanisms are unknown, limiting available treatments. The...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer and Skin Lesions
• Share to Hair Growth and Disorders
• Share to Skin and Cellular Biology Research