Article
Sodium excretion as a modulator of genetic associations with cardiovascular phenotypes in the European Project on Genes in Hypertension.
Journal of hypertension - 1 Feb 2006
Kuznetsova Tatiana, Staessen Jan A, Brand Eva, Cwynar Marcin, Stolarz Katarzyna, Thijs Lutgarde, Tikhonoff Valérie, Wojciechowska Wiktoria, Babeanu Speranta, Brand-Herrmann Stefan-Martin, Casiglia Edoardo, Filipovský Jan, Grodzicki Tomasz, Nikitin Yuri, Peleska Jan, Struijker-Boudier Harry, Bianchi Giuseppe, Kawecka-Jaszcz Kalina
Abstract excerpt
Hypertension is a chronic age-related disorder, affecting nearly 20% of all adult Europeans. This disease entails debilitating cardiovascular complications and is the leading cause for drug prescriptions in Europeans older than 50 years. Intensive research over the past two decades has so far failed to identify common genetic polymorphisms with a major impact on blood pressure or associated cardiovascular...
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