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Article

A comparison of univariate, bivariate, and trivariate whole-genome linkage screens of genetically correlated electrophysiological endophenotypes.

BMC genetics - 30 Dec 2005

Warren Diane M, Dyer Thomas D, Peterson Charles P, Mahaney Michael C, Blangero John, Almasy Laura

Abstract excerpt

We used a maximum-likelihood based multipoint linkage approach implemented in SOLAR to examine simultaneously linkage for three electrophysiological endophenotypes from the Collaborative Study of the Genetics of Alcoholism: TTTH1, TTTH2, and TTTH3. These endophenotypes have been identified as markers of alcohol dependence susceptibility. Data were from 905 individuals in 143 families. Measured covariates...

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Identifiers

PMID: 16451574
DOI: 10.1186/1471-2156-6-S1-S117
PMCID: PMC1866821

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