Article
Deficiency of coagulation factor XIII A subunit caused by the dinucleotide deletion at the 5' end of exon III.
The Journal of clinical investigation - 1 Aug 1992
Kamura T, Okamura T, Murakawa M, Tsuda H, Teshima T, Shibuya T, Harada M, Niho Y
Abstract excerpt
A congenital deficiency of the coagulation Factor XIII A subunit (F XIII A) is a rare autosomal recessive disorder that is characterized by a life-long bleeding tendency complicated by a difficulty in healing. Thus far, no molecular genetic analysis of this disorder has been reported. In this stu...
Topics
- Alleles
- Base Sequence
- Factor XIII
- Factor XIII Deficiency
- Gene Expression
- Genes
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Pedigree
- Polymerase Chain Reaction
- RNA, Messenger