Article
Characteristics of the broader phenotype in autism: a study of siblings using the children's communication checklist-2.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2006
Bishop Dorothy V M, Maybery Murray, Wong Dana, Maley Alana, Hallmayer Joachim
Abstract excerpt
Non-autistic relatives of people with autistic disorder have an increased risk of social and communicative difficulties: this is known as the "broad phenotype." Better methods for characterizing the broad phenotype are needed to facilitate identification of risk genes for autism. 29 siblings of 20 children with autistic disorder, 13 siblings of 9 children with PDDNOS, and 46 typically developing control children...
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