Article
CCM2 expression parallels that of CCM1.
Stroke - 1 Feb 2006
Seker Askin, Pricola Katie L, Guclu Bulent, Ozturk Ali K, Louvi Angeliki, Gunel Murat
Abstract excerpt
BACKGROUND AND PURPOSE: Mutations in CCM2 (MGC4607 or malcavernin) cause familial cerebral cavernous malformation (CCM), an autosomal dominant neurovascular disease. Both the function of this molecule and the pathogenesis of the disease remain elusive. METHODS: We analyzed the mRNA expression of...
Topics
- Animals
- Blotting, Western
- Brain
- COS Cells
- Carrier Proteins
- Cells, Cultured
- Central Nervous System
- Cerebral Cortex
- Chlorocebus aethiops
- Endothelium, Vascular
- Humans
- Immunohistochemistry
- In Situ Hybridization
- KRIT1 Protein
- Mice
- Microtubule-Associated Proteins
- Muscle, Smooth
- Mutation