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[Comparison CCR5de132 mutation in the CCR5 gene frequencies in Russians, Tuvinians, and in different groups of HIV-infected individuals].

Genetika - 1 Nov 2005

Apriatin S A, Rakhmanaliev E R, Nikolaeva I A, Ruban S V, Vazykhova F G, Klimov E A, Sulimova G E, Sidorovich I G

Abstract excerpt

The 32-bp deletion (CCR5del32 mutation) in the CCR5 (chemokine (C-C motif) receptor 5) gene, encoding CCR5 chemokine receptor, is one of the factors determining natural resistance to human immunodeficiency virus (HIV-1) infection. In the present study, the samples of Russians (n = 107), Tuvinians (n = 50), and HIV-infected individuals were examined for the presence of CCR5del32 mutation in the CCR5 gene. The...

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PMID: 16358723

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CCR5

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