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Article

Selection of Nonapoptotic Spermatozoa As a New Tool for Enhancing Assisted Reproduction Outcomes: An In Vitro Model1

23 Nov 2005

Abstract excerpt

Magnetic cell sorting (MACS) using annexin V-conjugated microbeads eliminates apoptotic spermatozoa based on the externalization of phosphatidylserine residues. The procedure delivers two sperm fractions: annexin V-negative (nonapoptotic) and annexin V-positive (apoptotic). Our aim was to determine whether the sperm fertilizing potential can be improved by selecting a nonapoptotic fraction using MACS. Semen...

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PMID: 16306419
DOI: 10.1095/biolreprod.105.046607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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