Article
Phylogenetic engineering at an interface between large and small subunits imparts land-plant kinetic properties to algal Rubisco.
Proceedings of the National Academy of Sciences of the United States of America - 22 Nov 2005
Spreitzer Robert J, Peddi Srinivasa R, Satagopan Sriram
Abstract excerpt
Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalyzes the rate-limiting step of photosynthetic CO(2) fixation and, thus, limits agricultural productivity. However, Rubisco enzymes from different species have different catalytic constants. If the structural basis for such differences were known, a rationale could be developed for genetically engineering an improved enzyme. Residues at the bottom of...
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