Article
Higher efficacy of sequential therapy with interferon-alpha and lamivudine combination compared to lamivudine monotherapy in HBeAg positive chronic hepatitis B patients.
The American journal of gastroenterology - 1 Nov 2005
Sarin Shiv Kumar, Kumar Manoj, Kumar Rakesh, Kazim Syed Naqui, Guptan Rajkumar Chander, Sakhuja Puja, Sharma Barjesh Chander
Abstract excerpt
BACKGROUND: Monotherapy with interferon (IFN) or lamivudine is effective in a limited proportion of chronic hepatitis B (CHB) patients. A sequential combination may have better therapeutic effects by sustained viral suppression combined with immunomodulation. AIM: To compare the efficacy of sequential lamivudine and IFN therapy versus lamivudine monotherapy in HBeAg positive CHB patients. PATIENTS AND METHODS:...
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