Article
Human gene therapy: present and future.
Breast cancer research and treatment - 1 Jan 1992
Kay M A, Ponder K P, Woo S L
Abstract excerpt
The hematopoietic system and the liver are two primary target organs for attempting somatic gene therapy of hereditary deficiencies. Several leading laboratories have recently been able to demonstrate that bone marrow cells from rodents and non-human primates can be successfully transduced with foreign genes, resulting in the functional expression of these genes in culture. The genetically reconstituted cells can...
Topics
- Animals
- Dogs
- Forecasting
- Genetic Therapy
- Humans
- Liver Transplantation
- Models, Biological
- Phenotype
- Recombination, Genetic
- Retroviridae Proteins
- Transfection
- alpha 1-Antitrypsin