Article
Centromere-proximal differentiation and speciation in Anopheles gambiae.
Proceedings of the National Academy of Sciences of the United States of America - 1 Nov 2005
Stump Aram D, Fitzpatrick Meagan C, Lobo Neil F, Traoré Sékou, Sagnon N'Fale, Costantini Carlo, Collins Frank H, Besansky Nora J
Abstract excerpt
The M and S molecular forms of Anopheles gambiae are undergoing speciation as they adapt to heterogeneities in the environment, spreading malaria in the process. We hypothesized that their divergence despite gene flow is facilitated by reduced recombination at the centromeric (proximal) end of the X chromosome. We sequenced introns from 22 X chromosome genes in M and S from two locations of West Africa where the...
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