Article
[On the association of tumor necrosis factor-alpha gene polymorphisms with the susceptibility to silicosis].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Sept 2005
Wang De-Jun, Yang Yue-Lin, Xia Qing-Jie, Lan Ya-Jia, Wang Mian-Zhen, Zhang Xiao-Qing, Han Ji-Ping, Zhu Qi-Shang, Sun Min
Abstract excerpt
OBJECTIVE: To find out whether -308 and -238 locus (G --> A) mutation within the tumor necrosis factor-alpha gene (TNF-alpha) promoter region are associated with susceptibility to silicosis in the Han population of southwest China. METHODS: Governed by the principles of voluntatiness and cooperation, 75 patients with silicosis and 137 control with silica-exposure but without silicosis were recruited, and...
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