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Gene‐based treatment of motor neuron diseases

14 Oct 2005

Abstract excerpt

Motor neuron diseases (MND), such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), are progressive neurodegenerative diseases that share the common characteristic of upper and/or lower motor neuron degeneration. Therapeutic strategies for MND are designed to confer neuroprotection, using trophic factors, anti-apoptotic proteins, as well as antioxidants and anti-excitotoxicity agents....

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PMID: 16228969
DOI: 10.1002/mus.20439

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