Article
The detection of shared and ancestral polymorphisms.
Genetical research - 1 Oct 2005
Charlesworth Brian, Bartolomé Carolina, Noël Véronique
Abstract excerpt
There is increasing evidence that closely related species contain many polymorphisms that were present in their common ancestral species. Use of a more distant relative as an outgroup increases the ability to detect such ancestral polymorphisms. We describe a method for further improving estimates of the fraction of polymorphisms that are ancestral, and illustrate this with reference to data on Drosophila...
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