Article
[Familial primary generalized epilepsy and drug (anticonvulsant)-induced systemic lupus erythematosus--a family study].
Zeitschrift fur Rheumatologie - 1 Jan 2000
Quietzsch J, Baumgarten C
Abstract excerpt
We report a 12-year study of a family with high mortality rate due to primary generalized epilepsy. During indicated and non-indicated therapy with anticonvulsive drugs (succinimides and hydantoines) there developed symptoms of systematic lupus erythematosus. The value of controlled immunological and genetic markers is discussed.
Topics
- Adolescent
- Adult
- Anticonvulsants
- Child
- Electroencephalography
- Epilepsy, Generalized
- Female
- HLA Antigens
- Humans
- Lupus Erythematosus, Systemic
- Male
- Pedigree
