Article
Possible interactions of the endothelial constitutive nitric oxide synthase genotype with alcohol drinking and walking time for high serum uric acid levels among Japanese.
Metabolism: clinical and experimental - 1 Oct 2005
Nishio Kazuko, Suzuki Koji, Ito Yoshinori, Naito Mariko, Yamamoto Kazuhito, Tamakoshi Akiko, Hamajima Nobuyuki
Abstract excerpt
A variable number of tandem repeat polymorphism located in intron 4 of the gene for endothelial constitutive nitric oxide synthase (ecNOS) is reported to be significantly associated with the nitric oxide level, which influences serum uric acid (SUA). To cast light on any association between the polymorphism and hyperuricemia, as well as gene-environment interactions, a cross-sectional study was conducted for 703...
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