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Article

Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: systematic evidence review for the U.S. Preventive Services Task Force.

Annals of internal medicine - 6 Sept 2005

Nelson Heidi D, Huffman Laurie Hoyt, Fu Rongwei, Harris Emily L

Abstract excerpt

BACKGROUND: Clinically significant mutations of BRCA1 and BRCA2 genes are associated with increased susceptibility for breast and ovarian cancer. Although these mutations are uncommon, public interest in testing for them is growing. PURPOSE: To determine benefits and harms of screening for inherited breast and ovarian cancer susceptibility in the general population of women without cancer presenting for primary...

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Identifiers

PMID: 16144895
DOI: 10.7326/0003-4819-143-5-200509060-00012

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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