Article
Analysis of LRRK 2 G 2019 S and I 2020 T mutations in Parkinson's disease.
Neuroscience letters - 16 Dec 2005
Bialecka Monika, Hui Shen, Klodowska-Duda Gabriela, Opala Grzegorz, Tan Eng-King, Drozdzik Marek
Abstract excerpt
Mutations in the leucine-rich repeat kinase 2 (LRRK 2), encoding dardarin protein, have been demonstrated to be linked to autosomal dominant Parkinson's disease (PD). In the present study the entire exon 41 of LRRK 2 gene was evaluated in a series of 174 PD patients recruited from Polish population, aged at the time of diagnosis 54.0+/-39.1 years, 21 of them had positive family history of PD with mean onset of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.