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Article

Inactivation of organellar glutamyl- and seryl-tRNA synthetases leads to developmental arrest of chloroplasts and mitochondria in higher plants.

The Journal of biological chemistry - 4 Nov 2005

Kim Yu-Kyung, Lee Jae-Yong, Cho Hye Sun, Lee Sang Sook, Ha Hyun Jung, Kim Sunghoon, Choi Doil, Pai Hyun-Sook

Abstract excerpt

Aminoacyl-tRNA synthetases (ARSs) are key enzymes involved in protein translation, and both cytosolic and organellar forms are present in the genomes of eukaryotes. In this study, we investigated cellular effects of depletion of organellar forms of ARS using virus-induced gene silencing (VIGS) in Nicotiana benthamiana. VIGS of NbERS and NbSRS, which encode organellar GluRS and SerRS, respectively, resulted in a...

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PMID: 16107332
DOI: 10.1074/jbc.M504805200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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