Article
Genetic predispositions for thromboembolism as a possible etiology for gastroschisis.
American journal of obstetrics and gynecology - 1 Aug 2005
Cardonick Elyce, Broth Richard, Kaufmann Marion, Seaton Jennifer, Henning Doreen, Roberts Nancy, Wapner Ronald
Abstract excerpt
OBJECTIVE: Occlusion of the omphalomesenteric artery in utero, leading to disruption of the umbilical ring with subsequent herniation of intestines, has been proposed as the mechanism by which gastroschisis occurs. We hypothesized that affected fetuses have a predisposition to arterial or venous thromboembolism. STUDY DESIGN: Thirty-one children born with gastroschisis were tested for Factor V Leiden,...
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