Article
Donor origin of BK virus in renal transplantation and role of HLA C7 in susceptibility to sustained BK viremia.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Sept 2005
Bohl Daniel L, Storch Gregory A, Ryschkewitsch Caroline, Gaudreault-Keener Monique, Schnitzler Mark A, Major Eugene O, Brennan Daniel C
Abstract excerpt
In a previous study, we performed serial BK virus (BKV), polymerase chain reaction (PCR) and detected active BKV infection in 70 (35.4%) of 198 renal transplant recipients. In the current study, pre-transplant donor and recipient samples were analyzed for BKV antibody titer and HLA alleles. Donor antibody titer was inversely proportional to onset of viruria, p<0.001, directly proportional to duration of viruria,...
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