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Sperm DNA fragmentation: threshold value in male fertility

5 Aug 2005

Abstract excerpt

BACKGROUND: The extent of sperm DNA fragmentation, which can be measured by the TUNEL assay, is one of the determinants of male fertility. However, the clinical application of this test to in-vivo situations is difficult owing to the absence of a statistically validated threshold value. METHODS: The aim of this study was to compare the results of TUNEL assay applied to semen samples from men of proven fertility...

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PMID: 16085665
DOI: 10.1093/humrep/dei231

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